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Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome

OBJECTIVE: Neonatal abstinence syndrome (NAS)—a clinical entity of infants from in utero exposure to psychoactive xenobiotic and buprenorphine—has been successfully used to treat NAS. However, nothing is known about the pharmacokinetics (PK) of buprenorphine in neonates with NAS. To our knowledge, t...

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Détails bibliographiques
Publié dans:Pharmacotherapy
Auteurs principaux: Ng, Chee M., Dombrowsky, Erin, Lin, Hopi, Erlich, Michelle E., Moody, David E., Barrett, Jeffrey S., Kraft, Walter K.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119858/
https://ncbi.nlm.nih.gov/pubmed/26172282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1610
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