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Population Pharmacokinetic Model of Sublingual Buprenorphine in Neonatal Abstinence Syndrome

OBJECTIVE: Neonatal abstinence syndrome (NAS)—a clinical entity of infants from in utero exposure to psychoactive xenobiotic and buprenorphine—has been successfully used to treat NAS. However, nothing is known about the pharmacokinetics (PK) of buprenorphine in neonates with NAS. To our knowledge, t...

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Detalhes bibliográficos
Publicado no:Pharmacotherapy
Main Authors: Ng, Chee M., Dombrowsky, Erin, Lin, Hopi, Erlich, Michelle E., Moody, David E., Barrett, Jeffrey S., Kraft, Walter K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119858/
https://ncbi.nlm.nih.gov/pubmed/26172282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1610
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