K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells

Toxoplasma gondii is the most common protozoan parasitic infection in man. Gamma interferon (IFNγ) activates haematopoietic and non-haematopoietic cells to kill the parasite and mediate host resistance. IFNγ-driven host resistance pathways and parasitic virulence factors are well described in mice,...

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Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Clough, Barbara, Wright, Joseph D., Pereira, Pedro M., Hirst, Elizabeth M., Johnston, Ashleigh C., Henriques, Ricardo, Frickel, Eva-Maria
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119857/
https://ncbi.nlm.nih.gov/pubmed/27875583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006027
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