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Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial

OBJECTIVES: Talimogene laherparepvec is the first oncolytic immunotherapy to receive approval in Europe, the USA and Australia. In the randomized, open-label Phase III OPTiM trial (NCT00769704), talimogene laherparepvec significantly improved durable response rate (DRR) versus granulocyte-macrophage...

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書目詳細資料
發表在:Onco Targets Ther
Main Authors: Harrington, Kevin J, Andtbacka, Robert HI, Collichio, Frances, Downey, Gerald, Chen, Lisa, Szabo, Zsolt, Kaufman, Howard L
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119624/
https://ncbi.nlm.nih.gov/pubmed/27895500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S115245
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