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Characterization of fiber-optic light delivery and light-induced temperature changes in a rodent brain for precise optogenetic neuromodulation

Understanding light intensity and temperature increase is of considerable importance in designing or performing in vivo optogenetic experiments. Our study describes the optimal light power at target depth in the rodent brain that would maximize activation of light-gated ion channels while minimizing...

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Bibliografiska uppgifter
I publikationen:Biomed Opt Express
Huvudupphovsmän: Shin, Younghoon, Yoo, Minsu, Kim, Hyung-Sun, Nam, Sung-Ki, Kim, Hyoung-Ihl, Lee, Sun-Kyu, Kim, Sohee, Kwon, Hyuk-Sang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Optical Society of America 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119587/
https://ncbi.nlm.nih.gov/pubmed/27895987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.7.004450
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