Parallel reverse genetic screening in mutant human cells using transcriptomics

Reverse genetic screens have driven gene annotation and target discovery in model organisms. However, many disease‐relevant genotypes and phenotypes cannot be studied in lower organisms. It is therefore essential to overcome technical hurdles associated with large‐scale reverse genetics in human cel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Syst Biol
Prif Awduron: Gapp, Bianca V, Konopka, Tomasz, Penz, Thomas, Dalal, Vineet, Bürckstümmer, Tilmann, Bock, Christoph, Nijman, Sebastian MB
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119491/
https://ncbi.nlm.nih.gov/pubmed/27482057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20166890
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