Reconstitution of high-affinity opioid agonist binding in brain membranes.
In synaptosomal membranes from rat brain cortex, the mu selective agonist [3H]dihydromorphine in the absence of sodium, and the nonselective antagonist [3H]naltrexone in the presence of sodium, bound to two populations of opioid receptor sites with Kd values of 0.69 and 8.7 nM for dihydromorphine, a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1848695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2171 |
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