Effect of High N-Acetylcysteine Concentrations on Antibiotic Activity against a Large Collection of Respiratory Pathogens

The effect of high N-acetylcysteine (NAC) concentrations (10 and 50 mM) on antibiotic activity against 40 strains of respiratory pathogens was investigated. NAC compromised the activity of carbapenems (of mostly imipenem and, to lesser extents, meropenem and ertapenem) in a dose-dependent fashion. W...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Landini, Giulia, Di Maggio, Tiziana, Sergio, Francesco, Docquier, Jean-Denis, Rossolini, Gian Maria, Pallecchi, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119039/
https://ncbi.nlm.nih.gov/pubmed/27736757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01334-16
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