A Novel Genome-Editing Platform for Drug-Resistant Acinetobacter baumannii Reveals an AdeR-Unrelated Tigecycline Resistance Mechanism

Infections with the Gram-negative coccobacillus Acinetobacter baumannii are a major threat in hospital settings. The progressing emergence of multidrug-resistant clinical strains significantly reduces the treatment options for clinicians to fight A. baumannii infections. The current lack of robust m...

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發表在:Antimicrob Agents Chemother
Main Authors: Trebosc, Vincent, Gartenmann, Sarah, Royet, Kevin, Manfredi, Pablo, Tötzl, Marcus, Schellhorn, Birgit, Pieren, Michel, Tigges, Marcel, Lociuro, Sergio, Sennhenn, Peter C., Gitzinger, Marc, Bumann, Dirk, Kemmer, Christian
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Mechanisms of Resistance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119006/
https://ncbi.nlm.nih.gov/pubmed/27671072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01275-16
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