Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

Pseudomonas aeruginosa is the major microorganism colonizing the respiratory epithelium in cystic fibrosis (CF) sufferers. The widespread use of available antibiotics has drastically reduced their efficacy, and antimicrobial peptides (AMPs) are a promising alternative. Among them, the frog skin-deri...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Cappiello, Floriana, Di Grazia, Antonio, Segev-Zarko, Li-av, Scali, Silvia, Ferrera, Loretta, Galietta, Luis, Pini, Alessandro, Shai, Yechiel, Di, Y. Peter, Mangoni, Maria Luisa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119005/
https://ncbi.nlm.nih.gov/pubmed/27671059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00904-16
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