Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

Pseudomonas aeruginosa is the major microorganism colonizing the respiratory epithelium in cystic fibrosis (CF) sufferers. The widespread use of available antibiotics has drastically reduced their efficacy, and antimicrobial peptides (AMPs) are a promising alternative. Among them, the frog skin-deri...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Cappiello, Floriana, Di Grazia, Antonio, Segev-Zarko, Li-av, Scali, Silvia, Ferrera, Loretta, Galietta, Luis, Pini, Alessandro, Shai, Yechiel, Di, Y. Peter, Mangoni, Maria Luisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119005/
https://ncbi.nlm.nih.gov/pubmed/27671059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00904-16
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