Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

Pseudomonas aeruginosa is the major microorganism colonizing the respiratory epithelium in cystic fibrosis (CF) sufferers. The widespread use of available antibiotics has drastically reduced their efficacy, and antimicrobial peptides (AMPs) are a promising alternative. Among them, the frog skin-deri...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cappiello, Floriana, Di Grazia, Antonio, Segev-Zarko, Li-av, Scali, Silvia, Ferrera, Loretta, Galietta, Luis, Pini, Alessandro, Shai, Yechiel, Di, Y. Peter, Mangoni, Maria Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119005/
https://ncbi.nlm.nih.gov/pubmed/27671059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00904-16
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