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Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation

Purpose: The purpose of this study was to investigate the profile of histone deacetylase (HDAC) activity and expression in osteosarcoma cells and tissues from osteosarcoma patients and to examine the mechanism by which a histone deacetylase (HDAC) inhibitor, Trichostatin A (TSA), promotes the apopto...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Deng, Zhantao, Liu, Xiaozhou, Jin, Jiewen, Xu, Haidong, Gao, Qian, Wang, Yong, Zhao, Jianning
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118776/
https://ncbi.nlm.nih.gov/pubmed/27877082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.16569
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