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Transcobalamin 776C→G polymorphism is associated with peripheral neuropathy in elderly individuals with high folate intake(1)(2)(3)

Background: The 776C→G polymorphism of the vitamin B-12 transport protein transcobalamin gene (TCN2) (rs1801198; Pro259Arg) is associated with a lower holotranscobalamin concentration in plasma. This effect may reduce the availability of vitamin B-12 to tissues even when vitamin B-12 intake is adequ...

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Detalhes bibliográficos
Publicado no:Am J Clin Nutr
Main Authors: Sawaengsri, Hathairat, Bergethon, Peter R, Qiu, Wei Qiao, Scott, Tammy M, Jacques, Paul F, Selhub, Jacob, Paul, Ligi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118734/
https://ncbi.nlm.nih.gov/pubmed/27733392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.116.139030
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