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Targeted delivery system for cancer cells consist of multiple ligands conjugated genetically modified CCMV capsid on doxorubicin GNPs complex

Targeted nano-delivery vehicles were developed from genetically modified Cowpea chlorotic mottle virus (CCMV) capsid by ligands bioconjugation for efficient drug delivery in cancer cells. RNA binding (N 1-25aa) and β-hexamer forming (N 27-41aa) domain of capsid was selectively deleted by genetic eng...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barwal, Indu, Kumar, Rajiv, Kateriya, Suneel, Dinda, Amit Kumar, Yadav, Subhash Chandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118717/
https://ncbi.nlm.nih.gov/pubmed/27872483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37096
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