Combined administration of anisodamine and neostigmine rescued acute lethal crush syndrome through α7nAChR-dependent JAK2-STAT3 signaling

Previously we showed that Ani (anisodamine)/Neo (neostigmine) combination produced anti-shock effect via activating α7 nicotinic acetylcholine receptor (α7nAChR). In this study, we aim to investigate the therapeutic effect and underlying mechanisms of Ani/Neo combination in acute lethal crush syndro...

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Pubblicato in:Sci Rep
Autori principali: Xu, Zhe-Qi, Shao, Bo-Zong, Ke, Ping, Liu, Jian-Guo, Liu, Guo-Ku, Chen, Xiong-Wen, Su, Ding-Feng, Liu, Chong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118690/
https://ncbi.nlm.nih.gov/pubmed/27874086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37709
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