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Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma

B cells are prominent components of human solid tumours, but activation status and functions of these cells in human cancers remain elusive. Here we establish that over 50% B cells in hepatocellular carcinoma (HCC) exhibit an FcγRII(low/−) activated phenotype, and high infiltration of these cells po...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ouyang, Fang-Zhu, Wu, Rui-Qi, Wei, Yuan, Liu, Rui-Xian, Yang, Dong, Xiao, Xiao, Zheng, Limin, Li, Bo, Lao, Xiang-Ming, Kuang, Dong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118541/
https://ncbi.nlm.nih.gov/pubmed/27853178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13453
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