Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway

The development of chemoresistance to cisplatin regimens causes a poor prognosis in patients with advanced NSCLC. The role of noncanonical Wnt signaling in the regulation of properties of lung cancer stem cells and chemoresistance was interrogated, by accessing capacities of cell proliferation, migr...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Yang, Jiali, Zhang, Kangjian, Wu, Jing, Shi, Juan, Xue, Jing, Li, Jing, Chen, Juan, Zhu, Yongzhao, Wei, Jun, He, Jinxi, Liu, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118537/
https://ncbi.nlm.nih.gov/pubmed/27895670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1690896
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