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Connecting Sarcomere Protein Mutations to Pathogenesis in Cardiomyopathies: The Development of “Disease in a Dish” Models

Recent technological and protocol developments have greatly increased the ability to utilize stem cells transformed into cardiomyocytes as models to study human heart muscle development and how this is affected by disease associated mutations in a variety of sarcomere proteins. In this perspective w...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zaunbrecher, Rebecca, Regnier, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118458/
https://ncbi.nlm.nih.gov/pubmed/27920728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00566
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