Knock-down of the methyltransferase Kmt6 relieves H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi

Filamentous fungi produce a vast array of secondary metabolites (SMs) and some play a role in agriculture or pharmacology. Sequencing of the rice pathogen Fusarium fujikuroi revealed the presence of far more SM-encoding genes than known products. SM production is energy-consuming and thus tightly re...

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Vydáno v:Environ Microbiol
Hlavní autoři: Studt, Lena, Rösler, Sarah M., Burkhardt, Immo, Arndt, Birgit, Freitag, Michael, Humpf, Hans-Ulrich, Dickschat, Jeroen S., Tudzynski, Bettina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118082/
https://ncbi.nlm.nih.gov/pubmed/27348741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1462-2920.13427
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