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Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics

PURPOSE: We evaluated efficacy and tolerability of the combination of ofatumumab and lenalidomide in patients with relapsed/refractory chronic lymphocytic leukemia (CLL), and explored whether immune system characteristics could influence the response to treatment. EXPERIMENTAL DESIGN: Thirty-four pa...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Vitale, Candida, Falchi, Lorenzo, ten Hacken, Elisa, Gao, Hui, Shaim, Hila, Van Roosbroeck, Katrien, Calin, George, O'Brien, Susan, Faderl, Stefan, Wang, Xuemei, Wierda, William G., Rezvani, Katayoun, Reuben, James M., Burger, Jan A., Keating, Michael J., Ferrajoli, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118034/
https://ncbi.nlm.nih.gov/pubmed/26733610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2476
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