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Feasibility of imaging of epidermal growth factor receptor expression with ZEGFR:2377 affibody molecule labeled with (99m)Tc using a peptide-based cysteine-containing chelator

The epidermal growth factor receptor (EGFR) is overexpressed in a number of malignant tumors and is a molecular target for several specific anticancer antibodies and tyrosine kinase inhibitors. The overexpression of EGFR is a predictive biomarker for response to several therapy regimens. Radionuclid...

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Bibliografski detalji
Izdano u:Int J Oncol
Glavni autori: Andersson, Ken G., Oroujeni, Maryam, Garousi, Javad, Mitran, Bogdan, Ståhl, Stefan, Orlova, Anna, Löfblom, John, Tolmachev, Vladimir
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118000/
https://ncbi.nlm.nih.gov/pubmed/27748899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3721
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