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Synthesis of three-arm block copolymer poly(lactic-co-glycolic acid)–poly(ethylene glycol) with oxalyl chloride and its application in hydrophobic drug delivery

PURPOSE: Synthesis of star-shaped block copolymer with oxalyl chloride and preparation of micelles to assess the prospect for drug-carrier applications. MATERIALS AND METHODS: Three-arm star block copolymers of poly(lactic-co-glycolic acid) (3S-PLGA)–polyethylene glycol (PEG) were synthesized by rin...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhu, Xiaowei, Liu, Chao, Duan, Jianwei, Liang, Xiaoyu, Li, Xuanling, Sun, Hongfan, Kong, Deling, Yang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117906/
https://ncbi.nlm.nih.gov/pubmed/27895480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S119446
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