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A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation
INTRODUCTION: Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend...
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Gepubliceerd in: | Onco Targets Ther |
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Hoofdauteurs: | , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Dove Medical Press
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117892/ https://ncbi.nlm.nih.gov/pubmed/27895501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S118502 |
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