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A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation

INTRODUCTION: Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend...

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Bibliografische gegevens
Gepubliceerd in:Onco Targets Ther
Hoofdauteurs: Frithiof, Henrik, Aaltonen, Kristina, Rydén, Lisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117892/
https://ncbi.nlm.nih.gov/pubmed/27895501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S118502
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