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Selexipag in the treatment of pulmonary arterial hypertension: design, development, and therapy

Pulmonary arterial hypertension is characterized by abnormalities in the small pulmonary arteries including increased vasoconstriction, vascular remodeling, proliferation of smooth muscle cells, and in situ thrombosis. Selexipag, a novel, oral prostacyclin receptor agonist, has been shown to improve...

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Publicat a:Drug Des Devel Ther
Autors principals: Hardin, Elizabeth Ashley, Chin, Kelly M
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117890/
https://ncbi.nlm.nih.gov/pubmed/27895464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S103534
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