Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection

Piroxicam (PRX), a potent nonsteroidal anti-inflammatory drug, is prescribed to relieve postoperative and/or chronic joint pain. However, its oral administration often results in serious gastrointestinal adverse effects including duodenal ulceration. Thus, a novel cationic nanoparticle (NP) was expl...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kim, Sung Rae, Ho, Myoung Jin, Kim, Sang Hyun, Cho, Ha Ra, Kim, Han Sol, Choi, Yong Seok, Choi, Young Wook, Kang, Myung Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117887/
https://ncbi.nlm.nih.gov/pubmed/27895468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S118145
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