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Functional asymmetry and electron flow in the bovine respirasome

Respirasomes are macromolecular assemblies of the respiratory chain complexes I, III and IV in the inner mitochondrial membrane. We determined the structure of supercomplex I(1)III(2)IV(1) from bovine heart mitochondria by cryo-EM at 9 Å resolution. Most protein-protein contacts between complex I, I...

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Pubblicato in:eLife
Autori principali: Sousa, Joana S, Mills, Deryck J, Vonck, Janet, Kühlbrandt, Werner
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117854/
https://ncbi.nlm.nih.gov/pubmed/27830641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21290
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