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Inhibition of STAT3- and MAPK-dependent PGE(2) synthesis ameliorates phagocytosis of fibrillar β-amyloid peptide (1-42) via EP2 receptor in EMF-stimulated N9 microglial cells
BACKGROUND: Prostaglandin E(2) (PGE(2))-involved neuroinflammatory processes are prevalent in several neurological conditions and diseases. Amyloid burden is correlated with the activation of E-prostanoid (EP) 2 receptors by PGE(2) in Alzheimer’s disease. We previously demonstrated that electromagne...
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Publicado no: | J Neuroinflammation |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117690/ https://ncbi.nlm.nih.gov/pubmed/27871289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0762-9 |
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