Coexistence of iAMP21 and ETV6-RUNX1 fusion in an adolescent with B cell acute lymphoblastic leukemia: literature review of six additional cases

BACKGROUND: Intrachromosomal amplification of chromosome 21 (iAMP21) results from breakage-fusion-bridge cycles and chromothripsis is a distinct marker of a subgroup of B cell acute lymphoblastic leukemia (B-ALL) cases associated with a poor prognosis. iAMP21 accounts for 2% of pediatric B-ALL and o...

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Vydáno v:Mol Cytogenet
Hlavní autoři: Gu, Jun, Reynolds, Alexandra, Fang, Lianghua, DeGraffenreid, Corrie, Sterns, Kenneth, Patel, Keyur P., Medeiros, L. Jeffrey, Lin, Pei, Lu, Xinyan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117506/
https://ncbi.nlm.nih.gov/pubmed/27895713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0294-0
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