Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis

Profiling of RNA from mouse mammary epithelial cells (MECs) isolated on pregnancy day (P)14 and lactation day (L)2 revealed that the majority of differentially expressed microRNA declined precipitously between late pregnancy and lactation. The decline in miR-150, which exhibited the greatest fold-de...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Heinz, Richard E., Rudolph, Michael C., Ramanathan, Palani, Spoelstra, Nicole S., Butterfield, Kiel T., Webb, Patricia G., Babbs, Beatrice L., Gao, Hongwei, Chen, Shang, Gordon, Michael A., Anderson, Steve M., Neville, Margaret C., Gu, Haihua, Richer, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117217/
https://ncbi.nlm.nih.gov/pubmed/27729410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.139642
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