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Rnd3-induced cell rounding requires interaction with Plexin-B2

Rnd proteins are atypical members of the Rho GTPase family that induce actin cytoskeletal reorganization and cell rounding. Rnd proteins have been reported to bind to the intracellular domain of several plexin receptors, but whether plexins contribute to the Rnd-induced rounding response is not know...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: McColl, Brad, Garg, Ritu, Riou, Philippe, Riento, Kirsi, Ridley, Anne J.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117210/
https://ncbi.nlm.nih.gov/pubmed/27656111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192211
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