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PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position
Disruption of epithelial architecture is a fundamental event during epithelial tumorigenesis. We show that the expression of the cancer-promoting phosphatase PRL-3 (PTP4A3), which is overexpressed in several epithelial cancers, in polarized epithelial MDCK and Caco2 cells leads to invasion and the f...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117205/ https://ncbi.nlm.nih.gov/pubmed/27656108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.190215 |
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