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Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos
In Xenopus laevis, bone morphogenetic proteins (Bmps) induce expression of the transcription factor Gata2 during gastrulation, and Gata2 is required in both ectodermal and mesodermal cells to enable mesoderm to commit to a hematopoietic fate. Here, we identify tril as a Gata2 target gene that is req...
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| Udgivet i: | Development |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117148/ https://ncbi.nlm.nih.gov/pubmed/27633996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.141812 |
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