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Unexpected, spontaneous conversion of a family of rats, from low-leukemic to high-leukemic inbred line.

From a nucleus of Sprague-Dawley rats received in 1960 from the National Institutes of Health, we have raised, by brother-to-sister mating, a colony of these animals. The incidence of leukemia in 313 females and 316 males was 1.6% and 1.2%, respectively. About 3 years ago, we observed a relatively h...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dreyfuss, Y, Gross, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2006145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2075
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