Cyclic di-AMP Released from Staphylococcus aureus Biofilm Induces a Macrophage Type I Interferon Response

Staphylococcus aureus is a leading cause of community- and nosocomial-acquired infections, with a propensity for biofilm formation. S. aureus biofilms actively skew the host immune response toward an anti-inflammatory state; however, the biofilm effector molecules and the mechanism(s) of action resp...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Gries, Casey M., Bruger, Eric L., Moormeier, Derek E., Scherr, Tyler D., Waters, Christopher M., Kielian, Tammy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116733/
https://ncbi.nlm.nih.gov/pubmed/27736778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00447-16
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