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Type II Secretion Is Necessary for Optimal Association of the Legionella-Containing Vacuole with Macrophage Rab1B but Enhances Intracellular Replication Mainly by Rab1B-Independent Mechanisms

Previously, we documented that type II secretion (T2S) promotes intracellular infection of macrophages by Legionella pneumophila. In the present study, we identified infection events that are modulated by T2S by comparing the behaviors of wild-type and T2S mutant bacteria in murine bone marrow-deriv...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: White, Richard C., Cianciotto, Nicholas P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116710/
https://ncbi.nlm.nih.gov/pubmed/27600508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00750-16
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