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N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma

Cluster of differentiation 147 (CD147), also known as extracellular matrix metalloproteinase inducer, is a transmembrane glycoprotein that mediates oncogenic processes partly through N-glycosylation modifications. N-glycosylation has been demonstrated to be instrumental for the regulation of CD147 f...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Li, Jiang-Hua, Huang, Wan, Lin, Peng, Wu, Bo, Fu, Zhi-Guang, Shen, Hao-Miao, Jing, Lin, Liu, Zhen-Yu, Zhou, Yang, Meng, Yao, Xu, Bao-Qing, Chen, Zhi-Nan, Jiang, Jian-Li
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116672/
https://ncbi.nlm.nih.gov/pubmed/27869218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35210
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