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Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease

Aspirin-exacerbated respiratory disease (AERD) is explained in part by over-expression of pro-inflammatory mediators including 5-lipoxygenase and leukotriene C(4) synthase (LTC(4)S) that results in constitutive over-production of cysteinyl leukotrienes (CysLTs). Mast cells and eosinophils are two ce...

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Détails bibliographiques
Publié dans:Immunol Allergy Clin North Am
Auteurs principaux: Steinke, John W., Payne, Spencer C, Borish, Larry
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116300/
https://ncbi.nlm.nih.gov/pubmed/27712766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.iac.2016.06.008
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