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Simtuzumab treatment of advanced liver fibrosis in HIV and HCV-infected adults: Results of a 6-month open-label safety trial

BACKGROUND: Chronic liver injury can result in fibrosis that may progress over years to end-stage liver disease. The most effective anti-fibrotic therapy is treatment of the underlying disease, however when not possible, interventions to reverse or slow fibrosis progression are needed. AIM: To study...

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Publicat a:Liver Int
Autors principals: Meissner, Eric G., McLaughlin, Mary, Matthews, Lindsay, Gharib, Ahmed M., Wood, Bradford J., Levy, Elliot, Sinkus, Ralph, Virtaneva, Kimmo, Sturdevant, Dan, Martens, Craig, Porcella, Stephen F., Goodman, Zachary D., Kanwar, Bittoo, Myers, Robert, Subramanian, Mani, Hadigan, Colleen, Masur, Henry, Kleiner, David E., Heller, Theo, Kottilil, Shyam, Kovacs, Joseph A., Morse, Caryn G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116256/
https://ncbi.nlm.nih.gov/pubmed/27232579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13177
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