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Defective autophagy leads to the suppression of stem-like features of CD271(+) osteosarcoma cells
BACKGROUND: As an important stress-response mechanism, autophagy plays crucial role in the tumor formation and drug resistance of cancer cells including osteosarcoma (OS). OS cancer stem cells (CSCs) also are considered a key factor of tumorigenesis, drug resistance and tumor recurrence. However, th...
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| Publicat a: | J Biomed Sci |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116184/ https://ncbi.nlm.nih.gov/pubmed/27863492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0297-5 |
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