Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model

Oligodendrocyte damage is a central event in the pathogenesis of the common neuroinflammatory condition, multiple sclerosis (MS). Where and how oligodendrocyte damage is initiated in MS is not completely understood. Here, we use a combination of light and electron microscopy techniques to provide a...

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Udgivet i:Nat Commun
Main Authors: Romanelli, Elisa, Merkler, Doron, Mezydlo, Aleksandra, Weil, Marie-Theres, Weber, Martin S., Nikić, Ivana, Potz, Stephanie, Meinl, Edgar, Matznick, Florian E. H., Kreutzfeldt, Mario, Ghanem, Alexander, Conzelmann, Karl-Klaus, Metz, Imke, Brück, Wolfgang, Routh, Matthew, Simons, Mikael, Bishop, Derron, Misgeld, Thomas, Kerschensteiner, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116090/
https://ncbi.nlm.nih.gov/pubmed/27848954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13275
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