PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis

A new metabolite, 2,4-dihydroxyquinoline (DHQ), was identified in cultures of the bacteria Pseudomonas aeruginosa and Burkholderia thailandensis. We found that the biosynthesis of DHQ correlates with the presence of a functional PqsA, which is a product of the pqsABCDE operon responsible for the syn...

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Veröffentlicht in:Biol Chem
Hauptverfasser: Lépine, Francois, Dekimpe, Valérie, Lesic, Biliana, Milot, Sylvain, Lesimple, Alain, Mamer, Orval A., Rahme, Laurence G., Déziel, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115913/
https://ncbi.nlm.nih.gov/pubmed/17655503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2007.100
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