Dissociation between iron accumulation and ferritin upregulation in the aged substantia nigra: attenuation by dietary restriction

Despite regulation, brain iron increases with aging and may enhance aging processes including neuroinflammation. Increases in magnetic resonance imaging transverse relaxation rates, R2 and R2*, in the brain have been observed during aging. We show R2 and R2* correlate well with iron content via dire...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Walker, Thomas, Michaelides, Christos, Ekonomou, Antigoni, Geraki, Kalotina, Parkes, Harold G, Suessmilch, Maria, Herlihy, Amy H, Crum, William R, So, Po-Wah
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115902/
https://ncbi.nlm.nih.gov/pubmed/27743512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101069
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