2-Aryl-5-carboxytetrazole as a New Photoaffinity Label for Drug Target Identification

[Image: see text] Photoaffinity labels are powerful tools for dissecting ligand–protein interactions, and they have a broad utility in medicinal chemistry and drug discovery. Traditional photoaffinity labels work through nonspecific C–H/X–H bond insertion reactions with the protein of interest by th...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Herner, András, Marjanovic, Jasmina, Lewandowski, Tracey M., Marin, Violeta, Patterson, Melanie, Miesbauer, Laura, Ready, Damien, Williams, Jon, Vasudevan, Anil, Lin, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115731/
https://ncbi.nlm.nih.gov/pubmed/27740749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b06645
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