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Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.

A marked decrease in the type I cAMP-dependent protein kinase regulatory subunit (RI alpha) and an increase in the type II protein kinase regulatory subunit (RII beta) correlate with growth inhibition and differentiation induced in a variety of types of human cancer cells, in vitro and in vivo, by s...

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Bibliographic Details
Main Authors: Tortora, G, Yokozaki, H, Pepe, S, Clair, T, Cho-Chung, Y S
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51156/
https://ncbi.nlm.nih.gov/pubmed/2000408
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