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Direct evidence that ganglioside is an integral component of the thyrotropin receptor.

Gangliosides were extracted from purified human and porcine thyrotropin (TSH) receptors (TSH-R) and were detected by probing with an 125I-labeled sialic acid-specific lectin, Limax flavus agglutinin. Gangliosides copurified with human and porcine TSH-R migrated between monosialoganglioside GM1 and d...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kielczynski, W, Harrison, L C, Leedman, P J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1991
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