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Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disease caused by interactions between environmental and genetic factors. The SMXA-5 mouse is a high-fat diet-induced fatty liver model established from SM/J and A/J strains. We have previously identified Fl1sa, a quantitative...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genet
Hauptverfasser: Suzuki, Miyako, Kobayashi, Misato, Ohno, Tamio, Kanamori, Shinsaku, Tateishi, Soushi, Murai, Atsushi, Horio, Fumihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114839/
https://ncbi.nlm.nih.gov/pubmed/27855657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0453-7
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