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Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway

BACKGROUND: In the fight against malaria, the discovery of chemical compounds with a novel mode of action and/or chemistry distinct from currently used drugs is vital to counteract the parasite’s known ability to develop drug resistance. Another desirable aspect is efficacy against gametocytes, the...

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Publicado no:Parasit Vectors
Main Authors: Fletcher, Sabine, Lucantoni, Leonardo, Sykes, Melissa L., Jones, Amy J., Holleran, John P., Saliba, Kevin J., Avery, Vicky M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114727/
https://ncbi.nlm.nih.gov/pubmed/27855724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-016-1860-3
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