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Reducing translation through eIF4G/IFG‐1 improves survival under ER stress that depends on heat shock factor HSF‐1 in Caenorhabditis elegans

Although certain methods of lowering and/or altering mRNA translation are associated with increased lifespan, the mechanisms underlying this effect remain largely unknown. We previously showed that the increased lifespan conferred by reducing expression of eukaryotic translation initiation factor 4G...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Howard, Amber C., Rollins, Jarod, Snow, Santina, Castor, Sarah, Rogers, Aric N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114698/
https://ncbi.nlm.nih.gov/pubmed/27538368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12516
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