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Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis

Myeloid-derived suppressor cells (MDSCs) are implicated in the promotion of tumor metastasis by protecting metastatic cancerous cells from immune surveillance and have thus been suggested as novel targets for cancer therapy. We demonstrate here that oral feeding with polyacetylenic glycosides (BP-E-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Wei, Wen-Chi, Lin, Sheng-Yen, Lan, Chun-Wen, Huang, Yu-Chen, Lin, Chih-Yu, Hsiao, Pei-Wen, Chen, Yet-Ran, Yang, Wen-Chin, Yang, Ning-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114612/
https://ncbi.nlm.nih.gov/pubmed/27857157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36663
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