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Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability

How neurons encode intracellular biochemical signalling cascades into electrical signals is not fully understood. Neurons in the central circadian clock in mammals provide a model system to investigate electrical encoding of biochemical timing signals. Here, using experimental and modelling approach...

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Publicat a:Nat Commun
Autors principals: Paul, Jodi R., DeWoskin, Daniel, McMeekin, Laura J., Cowell, Rita M., Forger, Daniel B., Gamble, Karen L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114562/
https://ncbi.nlm.nih.gov/pubmed/27841351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13470
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