Heart rate-induced modifications of concentric left ventricular hypertrophy: exploration of a novel therapeutic concept

Lowering the heart rate is considered to be beneficial in heart failure (HF) with reduced ejection fraction (HFrEF). In a dilated left ventricle (LV), pharmacological heart rate lowering is associated with a reduction in LV chamber size. In patients with HFrEF, this structural change is associated w...

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Klein, Franziska J., Bell, Stephen, Runte, K. Elisabeth, Lobel, Robert, Ashikaga, Takamuru, Lerman, Lilach O., LeWinter, Martin M., Meyer, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
Schlagworte:
Integrative Cardiovascular Physiology and Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114468/
https://ncbi.nlm.nih.gov/pubmed/27591220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00301.2016
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