Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases

Porcine epidemic diarrhea coronavirus (PEDV) is currently devastating the United States pork industry by causing an 80–100% fatality rate in infected piglets. Coronavirus spike proteins mediate virus entry into cells, a process that requires the spike proteins to be proteolytically activated. It has...

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Udgivet i:J Biol Chem
Main Authors: Liu, Chang, Ma, Yuanmei, Yang, Yang, Zheng, Yuan, Shang, Jian, Zhou, Yusen, Jiang, Shibo, Du, Lanying, Li, Jianrong, Li, Fang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114425/
https://ncbi.nlm.nih.gov/pubmed/27729455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740746
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